STRIDE vs. Generic Efinaconazole: Is There a Real Difference?

Efinaconazole is the active ingredient in Jublia, a prescription topical solution for toenail fungus (onychomycosis), and it's the treatment most patients are offered first. With generic efinaconazole now available, many assume the only real decision left is brand versus generic price. However, the more useful question should be whether an efinaconazole solution alone, brand or generic, is enough to clear the infection at all. STRIDEDUO™ treatment, which boasts an impressive 89% clinical success rate, can be a better solution for patients looking to eradicate onychomycosis from the root.

Generic vs. Brand: What's Actually the Same

Generic efinaconazole contains the same active ingredient as Jublia and must meet FDA bioequivalence standards. For most patients, brand-vs-generic comes down to cost, not clinical outcome; the real limitation lies elsewhere, and it's the same limitation STRIDE DUO™ was built to address, i.e., eradicating toenail fungus from the inside through terbinafine along with topical treatment.

Why Topical Efinaconazole Alone Often FallsShort

Clinical evidence gives an unequivocal message: only10-20% of patients with toenail fungus benefit from topical antifungals. As it turns out, the majority of individuals treated with an over-the-counter antifungal see no improvement at all or experience limited improvement before their condition recurs, often within 6 to 12 months. (Source)

STRIDE DUO™: Built Around That Exact Problem

The STRIDE DUO™ system is aimed at addressing three significant hurdles in treatment: the keratin shield of the nail, fungal biofilm protection, and spore dormancy that leads to recurrence of infection.

It does this with a "top-down and bottom-up" approach: ClearNail Renewal™ works topically to soften and penetrate the nail from above, while pulse-dosed oral terbinafine, 7 days on, roughly 90 days off, works systemically, persisting in the nail keratin with less total medication exposure than continuous dosing.

If topical treatment alone hasn't worked, a licensed provider can review your history and help determine whether a combination approach is right for you.

See If You Qualify

If the 89% STRIDE figure is restored anywhere, define exactly what “clinical success” means, identify the study/data source, sample size, endpoint and follow-up period, and have the claim reviewed for advertising substantiation.

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